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What clinical effectiveness “Viagra”?

According to numerous clinical research and drug testing for volunteers with different types of erectile dysfunction, including on our own data, sildenafila citrate has a fairly high efficiency. However, it should be stressed here some nuances.

Effectiveness “Viagra” very much depends on the type of erectile dysfunction, from opportunistic diseases. For example, if the vascular erectile dysfunction drug, quite effective, then, say, if the so-called venous drainage pathological results of its application is much worse.

Unfortunately, there is not, and indeed can not exist drug that can cure all diseases, or, as in our case, all kinds of erectile dysfunction. Not a panacea, and “Viagra”, which can help to a very large number of cases, but, unfortunately, not all patients.

“” Viagra is effective in patients with atherosclerosis, damage nerves going to receptacles sexual member, with sugar diabetes. Not too good, as we have said, the use of the drug in patients with venous drainage pathological existence. In each of these cases in treating the disease may help your doctor. Only a doctor can appoint the correct treatment and to find the best means. So we are quite spaghetti refer you to the people in white coats.



As conducted clinical trials of drugs?

According to the amount spent force and the means to test new drugs company Pfizer, perhaps a record. Judge for yourselves.

The product “Viagra” evaluated more than 3,000 men aged 19 to 87 years in erektilnyh dysfunction studies conducted throughout the world. The duration of the violations erektsy these patients averaged 5 years (from 6 months to 26 years), a penis was an organic disorder, psychogenic and mixed organic and psychogenic etiology. The results of these studies show that the drug, “Viagra” is effective to restore erectile function and improve the performance of successful sexual acts with large numbers of patients, including a number of diabetics, with damage to the spinal cord, other related clinical conditions, as well as patients Taking the same time a number of medications. The product “Viagra” acted in response to natural sexual stimulation to restore erectile function. On tied therapy noomalizatsii Mature reported 70-90% of patients who took drug, “Viagra”, and only 10-30% of patients receiving placebo (pustyshku). Doses drug “Viagra” from 50 to 100 mg well tolerated and vysokoeffektivny to restore erectile function in studies in which drug dosage can be adjusted depending on its efficiency and Portability (for example, in studies with a flexible dosage change). The results of more than 550 studies of patients receiving treatment at least over a year, very convincingly show that the effectiveness of the drug “Viagra” persisted for a long treatment.



It was invented “Viagra”?

In the history of medicine has a lot of facts, when the emergence of miraculous discoveries were the result of random observations or findings. Two of the most striking example so far is the discovery of X-ray radiation and antibiotics.

In 1895 German scientist Wilhelm Conrad Röntgen drew attention to the unusual green light effect in the dark items that shortly before that time were employed in the vicinity of high - cathode tubes. He also drew attention to what was happening zasvechivanie packed photographic film, which was also near a high employee tubes. These unexpected observations allowed ingenious physics suggest the existence of radiation, which had not previously been known to mankind. In the future, as we know, so bold was fully confirmed.

The history of antibiotics is the opening sequence even more amazing coincidence. In 1928, a British researcher Alexander Fleming accidentally discovered that a dirty mold destroyed almost all types of bacteria, which he grew for bacteriological experiments. However, rather than subjecting laboratory dishes for growing bacteria sterilization experiments and start anew, Fleming carefully studied the properties of dirty mold, which we now known under the name “Penicillin.” So were opened antibiotics, which carried out the coup in medicine.

Opening “Viagra” was, apparently, the third greatest “accidental” discoveries in medicine. This is evidenced by the fact that all of the kind described above, were awarded the Nobel Prize. The same high honors in autumn 1998 was awarded to researchers find, among other things, properties “drug Viagra.”

The history of “Viagra” started in 1992 in Britain, in the locality of Pfayzers Sendvich in pharmacological research firm Pfizer. ” Researchers conducting clinical trials of new medicinal substance-Tsitrata Sildenafila, which was developed as a means to treat a number of cardiac ailments. Scientists had hoped that the citrate sildenafila will boost blood to the heart muscle and reduce blood pressure. However, it was noted that citrate sildenafila not have a significant impact on either the blood circulation in heart muscle (myocardium), or on blood pressure. Parallel found that many male patients who participated in the study, refused to return the pills sildenafila, despite the end of the test. The reason for the denial of all these patients was an all-hosting, they noted a sharp improvement in the quality erektsy. Thus, despite the minimal impact of new drugs on blood circulation in the heart, sildenafil caused sizeable inflow of blood to the male genitalia.

Researchers pharmacological companies “Pfizer” listened to the unexpected properties tsitrata sildenafila with due care and attention have been able to recognize it a powerful tool in the fight against violations erektsy. The new drug, has been termed the “Viagra” name - was born as a result of a merger would be the words “Vigor” (power, energy, strength), and Niagara is the most powerful waterfall in North America.

Since 1993, began extensive clinical trials necessary to demonstrate the properties of “Viagra”. As a result of these tests has been demonstrated high efficiency “Viagra” to treat impotency, and high security of this drug. And as a legitimate finals-March 27, 1998 The Department of dollars on food and medicines approved the use of “Viagra”.



It solved the problem of impotency until recently?

Referring to the treatment of impotency, it is impossible not to mention the exotic ways such as the use of cooked dried powders penisov some animals vshivanii rib cartilage in sexual member, apply all possible erotic creams and ointments, as well as the use of cheese in the form of testicular young calves. Yes! All of these ways are not our invention, and in fact, they much more. And all of them at different times by different people applied, and some apply to this day. But it is exotic. And if seriously, today is the world’s treatment of two groups in the fight against erectile dysfunction. First, conservative activities (ie seksopatologicheskaya psychotherapy and rehabilitation, the use of different drugs, which include Viagra “and” mechanical devices to achieve erection), and secondly, operational activities - that is, all kinds of surgical procedures.

So, with regard to conservative measures. As already mentioned, in response to the previous question, the most well-known until recently drugs to combat impotence were papaverin, fentolamin and prostaglandiny group E1. All these products have a number of shortcomings that severely limit their use.

A chapter in the treatment of erectile dysfunction is the use of different technical devices. The basis of their prisasyvayuschie up all sorts of devices. The meaning of their actions very simple: Sexual member dresses transparent plastic bulb, which is connected by hose pump with a compact. The pump pumping air from the bulb, causing blood to the strengthening of the influx of sexually member and as a result pleasure. But this method of treatment in our time except rarity not be called. Because if a member of the puncture in the front sexually act where it is neither went, then detonated bulb, Penguin pumps before the intimate event in the personal lives of every person is already, in our view, too. But, nevertheless, there is really that, it seems, once again proves what people ready to make sacrifices to achieve full of joy sexuality.

With regard to surgical treatment, they can be divided into three categories:

Operation for sexual receptacle member, which are aimed at restoring normal blood inflow and outflow in sexual member (these operations are performed vascular surgeons). Such operations are particularly effective for young people who have experienced trauma to the pelvis bone damage to vessels that go to sex member.

Operation to remove a member warped sex (performed urology and cosmetic surgeons). These operations are widespread, because warped sexuality member can be removed only by surgically.

The operation of prosthetic member pescheristyh phone sex (also performed urology). These people need intervention with a gross fibrosis pescheristyh phone rescheduled after trauma, inflammation or long papaverina application in the form of injuries from sexual member.

As you can see, esteemed reader, the arsenal of treatments in this area of medicine quite broad and diverse. But all these methods on their effectiveness, accessibility and, most importantly, security can go either in comparison with the pill “Viagra”.



As Erection occurs?

According to Aristotle (384-322 Messrs. to He. E). Erection of sexual member come as a result of “filling his gas wonderful space.” Some Insiders say even the history of medicine that existed sculpture, in which women with razduvshimisya crushing hard trying to give the members of their sex beloved “gas”. This is easy!

If seriously, in order to answer this question very briefly, let me explain how member arranged sexual rights.

Sexual is a member of the root, body and the head. “The main device, which makes it possible to achieve erection, are pescheristye (kavernoznye) body. The basis of normal sexual function is a member of his blood and innervatsiya. The influx of blood in the body pescheristye carried out by paired rear arteries. Arteries and nerves are located on the sides of the central rear deep vein sexual member. In the last many feel vein, a member of the sexual envelopes. Powerful muscles fix to the root of sexual member of Bone pelvis and the front abdominal wall.

Pescheristye directly in the body of arterial blood comes from the deep arteries paired sexual member, and the waste from them spiral arteries (arteries that is, small-caliber). The role of the latter in the event of a sexual and maintain elasticity member crucial, as will be discussed below.

As already mentioned, the elasticity of sexual member during erection is achieved mainly through pescheristyh tel. The latter are composed of cells formed soedinitelno-tkannymi bulkheads and smooth muscles that make up the complex three-dimensional network.

The above purely descriptive sexual anatomy member who is in a state of complete relaxation is crucial for understanding the process of erection.

As members, located in a state of relaxation small arteries flowing into the cell phone pescheristyh, spazmirovany-ie narrowed by smaller muscle fibers voltage, which is in the blood melkokalibernom each dish. It is through such a compression of the blood did not reach the pescheristye sexual body member and he unbraced. So interesting physiological phenomenon - when a member of unbraced, his inner receptacles stretched, and hence the voltage very sexually members (ie, the emergence of Mature), it’s only when the vascular relaxation and is a member of sexual filled with blood. The process of filling the blood pescheristyh member phone sex occurs in response to sexual stimulation when the parent sends impulses in the brain nerve tissue in the end sexual member. It was those nerve impulses lead to the expansion of small arteries relieve sexual member.

The second important component, which is involved in the maintenance of normal sexual hardness is a member of venous drainage system. In any other sector of the human body, this vein vessels that carry blood from the body simply ottekaet, claiming a harmful substance. In all genders members on the other, because if venous blood simply ottekala of sexual member, he would never have “stood up”. Therefore, Mother Nature invented a remarkable device that scientists have named veno-zapiratelnym mechanism. The essence of it is very simple. When the expanded blood receptacles pescheristye gears in the body and they are increasing in size, it increases in size they are positioned soft thin veins, which are located between pescheristymi elastic bodies and bruises sheathing (see figure). Thus venous outflow of sexual member “blocked”, and begins to work again only when the blood flow ceases to pescheristye body (after the cessation of sexual stimulation) sex-member relaxed.

So when a man has sexual arousal his head brain sends signals nerve endings in the tissues of sexual member. This has resulted in the blood vessels expand sexual member, sharply increasing inflow of blood, which lost Erection begins. At the same time, narrowed vessels (veins), which usually occurs through the outflow of blood from sexually member. This combination of increased flow of blood to a member of the sexual and reducing its outflow leads to full erection. When sexual stimulation stopped, the outflow of blood from happening sexual member that gets in his relaxed state.

Thus, a mechanism is provided erect three components:

Sexual stimulation and transmission of impulses in the brain nerve end sexual member

Relaxation muscle fibers in the walls of small arteries within member pescheristyh phone sex

Block venous outflow

If blood vessels and nerves involved in the development of Erectile functioning correctly, the man could not achieve erection and support it.



As “Viagra” operates on the fortress of marriage bonds?

Interestingly, when Viagra came only in the sale within the United States of America, to seksopatologam vystroilas turn of the Concerned wives …. They, in fact, not without reason, seriously frightened of what their husbands-demure person, having been in the hands of such a “hellish” drug, and dumped their didst go for concubines. It seemed that if a man has long forgotten that this present sexual adventure, suddenly gaining strength and agilities young man, it must not fail to get a mistress, if (the horror!) And no one!

But later it turned out that all mothers fear noble families are without any foundation. It is a paradox at first glance, the family ties only strengthened Viagra. It turned out that the emergence of a confident person in the family-esteem, this father of the family contributes to the harmonization of relations between the partners. And a man in this situation prefer long, “tested” options sexual closeness is not seeking adventure on the side of questionable.

In addition, not be forgotten that “Viagra” began to use not only men but also women. In some cases, women are not able to reach orgasm in the past, in the admission of “Viagra” have become able to fully enjoy sex with proximity favorite person. Again, as numerous polls have shown that women prefer to engage in love with a person with whom they had lived together for many years.

In addition to the above considerations, we feel the same obvious that the number of divorces could be reduced by improving the quality of sexuality in family pairs. It is no secret that a great deal of the number of divorce cases are based on dissatisfaction with the spouses is in the sexual sphere.

So concerns to the integrity of families in the light of the emergence of erectile dysfunction pill seems to us, to put it mildly, false. Moreover, we would like to believe that gaining confidence in sexuality will strengthen family ties and mutual understanding between the spouses.



40 facts about sex … without knowing where they simply engage in improper

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1. male mice decide that the female arranges them as sexual partners for one second. There are many people all at the longest. We need 2 to 3 seconds to recognize in the running to meet a woman sexually attractive object. (Our photo editor for coping 0,004-0,006)

2. For women, it is generally protracted history. On reflection that seems to them whether the man sexually successful partner, they take time out in the entire 8 seconds *.

3. Mean woman believes that the preliminary affection should not hold less than a third of all sexual act. But somehow this figure varies greatly from country to country: if the NIPs, for example, is devoting a prelude to an average 40% of the time, the Brazilian ladies feel that, and 15% are more than Bueno. Maybe it from the fact that in Japan are much less important broadcast football matches and local men will not usually slow.

4. Average length of the vagina-14, see This heightened sensitivity only see the first 5 So if talking about the size of life in poor parts of the body (you will not believe, but it is the penis and refers to them), the diameter is vazhney length.

5. nerve receptors respond to touch on a lot more when they touch nereguliruemy and unexpected. Therefore, men who prefer to move in a single, seamless rhythmic pace, losing heavily in women’s eyes in comparison with the unpredictable and gusty partners who ably goes fast with the slow movement, with a sharp-smooth.

6. But when it moves to a climax partners, will be wiser not to seek goodness of the good, but stick to a predetermined rhythm, and depth of immersion - gun in the search for diversity is only discourage the girl, preventing her focus.

7. If it is a clitoris, not to be forgotten: that can be seen from the outside, only vertex iceberg. A slit is ingenious 5-7 cm length and let it is covert, but he immediately reported everything that happens nearby. For it is in the dense network of nerve leading to the end.

8. Nature loves all duplicate. Almost all animals in the nature of two eyes, two ears, the number of paired limbs and many internal organs. Here’s to women, such as type 2 immediately orgazma- klitoralny and vaginal. Of course, this apparent excesses, but it will certainly get.

9. At the senses and vaginal klitoralny orgazmy differ … it is difficult for us to imagine … .. but, in general, the difference between them about such as the impact on the head with a) a bottle, and b) taburetkoy. Ie the whole gamut of feelings raises complex, but here all the nuances of the case.

10. Klitoralny orgazm due to the outside stimulation clitoris, a very similar mechanism at the men’s actions. It starts with a light, all growing stimulation, after which leads to violent, but not prolonged (5-8 with a peak). Then stir immediately recedes (up to the full “and that hour, a pretty? Maybe postponed until all until tomorrow? “). However, unlike us, ladies can recover almost immediately, within a few minutes Lask, again raised up in the mood.

11. Vaginal orgazm caused stimulation clitoris and surrounding areas from the inside does not have such a pronounced peak, and it is very long (from 10 to up to half an hour). And orgazmy they can follow one after another without a break. Why women with the possibility of such dangers in their lives, to pro shops and halls Conservatory, rather than around the clock to have sex? That is the question modern science has no answer.

12. The number of live sperm in a sperm about 10 million

13. And to settle the whole planet from scratch, you would be required to test all 62 times orgazm.

14. The most common sexual position, “a missionary.” Every third sexual intercourse takes place in the world with its use. In the second place, “doggi-stayl”, the third - “lying on the side, the man at the rear.”

15. Sperm can remain alive in the body, about a hundred women hours. If, of course, not offend them and margantsovkoy postkoitalnymi vyginalnymi tablet.

16. So raznoyaytsovye twins can have different fathers. Moreover, no small number of doctors are aware of such cases.

17. Sperm can fall in swarms. Peter Brugger, neyrobiolog Medical Center, University of Zurich, long studied sperm, gonyaya them, as in the labyrinth of mice, and found that they prefer to move the command following the speshaschimi ahead brethren. Apparently, they are able to pass one another and capture some signals, but as it happens, is not known yet.

18. Looming ejaculation could delay, if slightly testicles Pull back and down. This movement reduces seed kanatiki that before increasing the maximum orgasm.

19. Conversely, offensive orgasm accelerate if the press to cut the palm of the testicles.

20. According to research specialists from Stanford University and the most incident fragrances for women are chopped cucumbers, chocolate, vanilla and svezhevypechennoy seller.

21. Point G there! (Well, you want to read the fifth time in a million is about the latest scientific discovery Grefenberga Doctor? Yes please, we do not mind being. Point G is a large accumulation nerve end, is located in the front wall of the vagina somewhere in the middle of its length. When directed this stimulation the area most women are feeling strong, tickling the incident. Some love it, but some, by the way, not very.)

22. And except for G there is a point K. Two pieces. This tiny two compaction on both sides of the right and left of the clitoris (at a distance of about 1 cm of it), which also operate the centers of sexual stimulation. And if lightly stroking their fingers, they tangibly cure.

23. Think, we finished with the alphabet? Do you think so in vain. In women, as in the Hungarian script, a lot of different characters. Take, for example, point C. It is, in fact, useful, but it is difficult nahodimaya thing. This tiny center will be located in the heart and cut represents barely noticeable bugorok. In a lengthy rhythmic clicking on it happen reduce muscle cut that lead to orgazmu.

24. Peak concentrations garmonov-androgenov (substances that cause women’s sexual attraction) is for 9-14 day after the start of menstruation. So if you sent to pharmacies for tampaksami, zaglyani together on the road in the print shop and buy kalendarik.

25. And “Viagra” and “Cialis” must be taken not earlier than one hour prior to the alleged sex. If you recently densely poobedal, nakin another 40 minutes. (Approximately three times as many slow dance intermittently to drink lemonade. Or poem recitation “Mtsyri.” Or 250 times in a row anecdote told about Shtirlitsa and raskoryaku. In general, will have to come up as poelegantnee kill time.)

26. By sex, female makaki-rezusa shouting so loudly, as a higher stage in the hierarchy staynoy took their partner. Thus, in the view of scientists, female raise its prestige in a hundred. (Note deputy. Gl.redaktora: “And this information is what the article to the topic? Not enough. Remove it out! After all, this simply insulting! ” )

27. Primerka operates on the heels of women bringing manner. First is the shoes. And in the second-, foot massage big fingers to guard unconditional erotic pleasure from the fact that at the base of the fingers point are responsible for prilivanie blood to the genitals. At least this was sure teachers ancient Chinese acupuncture schools.

28. What is your lighter touch, the more a woman would feel, in principle, during the preliminary Lask not even touch the leather will be enough to hold the fingers in a few mm above it. Pushing fingers to the skin, you can only influence on receptors located in the epidermis nepostredstvenno and sliding top. You will be busy mnogochislennnye microscopic voloski-antenny that will send signals to those sensory receptors, which otherwise would not be able to be Involved.

29. Breast very actively reacts to heat and cold. What warmer in the room, the softer and more it will become bigger and the nipples.

30. But even if in a room facing the Siberian cold in the excitation peaks Bust female can increase its volume by 25% through the active prilivaniya its blood.

31. average sexual act on this planet prodolzhaeisya 3.5 min. To the average f capable orgazmu woman to reach orgasm of the required minimum of 15-20 minutes. And we all wonder: where war, the stresses jaw ozone layer.

32. 20% of women have no gap occurs pristine virginity during the first sexual intercourse. This is called the third prichinami-libo congenital lack of virginity, either initially large holes in it, or its elastichnostyu.Vo 2 nd and 3 rd cases irretrievable breakdown occurs only during childbirth.

33. Only? European and American women would like a lifetime to have sex with the same partner. All of the remaining wanted to do, and try to fabricate.

34. A male figures loyalty still modest. Only 7% of totally monogamous dreamed citizens to limit odnoy- only woman for life. However another 25% saw the ideal that through trial and error to find their sole and never has it not changed.

35. For each 2-born gay lesbian alone.

36. The most powerful Erection byvae to sex. Almost immediately after the beginning of the process of inflow of blood to the penis is reduced and Erection is already 70-80% of the original.

37. This is not only normal, it is very correct, because very often eregirovanny penis is a woman rather than pleasant feelings. Indeed, virtually deprived of this body is very important flexibility and agility. (effect of prolonged high resilience usually emerges as the institute on high, and when afrodiziakov admission.)

38. Every 20 th women sometimes occur attacks vaginizma.Tak called spasmodic muscle compression vlagalischa.uschemlyayuschie penis, and causing pain and the man and woman. The best way to cope with the situation to calm down and try to relax. Both partneram.Pytatsya escape from the grip of fate not to be. There will be only worse. Gramotnee FIPRESCI polezhat will calmly. talk about something abstract, such as weather in Koala-Lumpure. When the excitation should be brought to a head cramps. (If not good and all very Koala-Lumpur spans over an hour, you must somehow get to the phone and dialed 03.

39. FIFA testicular temperature by 2 degrees below the rest of the body, even though there will be a little bit warmer. Sperm could not reach.

40. It’s still the main center stimulation in humans is in the brain. That is why some women may try orgazm only one literate lengthy kiss. (You, too, in 15 years, so ably).

MAXIM Magazine

June 2004




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